Top 100 Companies in Indiana

Indiana is home to a diverse economy with industries ranging from manufacturing and logistics to healthcare, technology, and agriculture. The state is a hub for some of the largest corporations in the United States. This article explores the top 100 companies in Indiana, offering insights into their influence, industries, and contributions to the state's economy. These companies not only dominate their respective fields but also shape Indiana's workforce and economy. Starting with the most prominent and influential companies, this reverse-chronological guide will highlight their achievements, leaving readers with a comprehensive understanding of what drives Indiana's corporate success.

Eli Lilly and Company

Founded in 1876, Eli Lilly is a global pharmaceutical leader based in Indianapolis. The company has been at the forefront of medical innovation, providing treatments for conditions such as diabetes, cancer, and mental health disorders. Eli Lilly's impact on Indiana cannot be overstated—with over 35,000 employees worldwide and a commitment to research, the company invests heavily in the local economy. The company is also known for its philanthropic efforts, particularly through the Lilly Endowment, which has contributed billions to education, healthcare, and community development in Indiana.

Cummins Inc.

Cummins, headquartered in Columbus, Indiana, is a global leader in diesel and alternative fuel engines. With a history dating back to 1919, Cummins has evolved into a powerhouse with operations in more than 190 countries. The company is a major employer in Indiana, with thousands of workers across its manufacturing plants and corporate offices. Cummins' commitment to sustainability and innovation has positioned it as a key player in the global transition to cleaner energy sources.

Company Name	Industry	Headquarters	Number of Employees
Eli Lilly	Pharmaceuticals	Indianapolis	35,000+
Cummins Inc.	Manufacturing (Engines)	Columbus	59,900

Anthem Inc.

A Fortune 500 company, Anthem is one of the largest health insurance providers in the United States, with its headquarters in Indianapolis. Anthem serves nearly 40 million Americans, making it a vital player in both the national healthcare system and Indiana's economy. Anthem's focus on technology and data-driven healthcare solutions sets it apart as an innovative leader in the health insurance industry.

Roche Diagnostics

Roche Diagnostics, part of the global Roche Group, operates its North American headquarters in Indianapolis. The company specializes in medical diagnostic equipment and technology, providing tools that are critical for laboratories worldwide. Roche’s investment in its Indiana facilities highlights its long-term commitment to innovation in healthcare.

Company Name	Industry	Headquarters	Annual Revenue
Anthem Inc.	Health Insurance	Indianapolis	$121.9 billion
Roche Diagnostics	Healthcare/Diagnostics	Indianapolis	$58.3 billion

Allison Transmission

Allison Transmission is a leading manufacturer of automatic transmissions for commercial and military vehicles, with headquarters in Indianapolis. Founded in 1915, the company has a long history of supplying high-performance transmissions worldwide. Allison is known for its innovation in both commercial and defense markets, employing thousands in Indiana and supporting numerous local suppliers.

Steel Dynamics Inc.

One of the largest steel producers in the United States, Steel Dynamics Inc. (SDI) is headquartered in Fort Wayne, Indiana. The company was founded in 1993 and has quickly risen to become a major player in the global steel industry. SDI is known for its sustainable practices, particularly its use of electric arc furnaces, which consume significantly less energy than traditional methods. The company employs more than 10,000 people, many of whom work in Indiana.

Company Name	Industry	Headquarters	Employees
Allison Transmission	Manufacturing (Transmissions)	Indianapolis	3,000+
Steel Dynamics Inc.	Steel Production	Fort Wayne	10,000+

Cook Group

Cook Group, a medical device company based in Bloomington, Indiana, has been a pioneer in the development of minimally invasive medical technologies since its founding in 1963. The company remains privately owned and has a global reach, with thousands of employees worldwide. Cook Group's contributions to healthcare innovation have placed Indiana on the map as a leader in life sciences.

Indiana University Health

Indiana University Health (IU Health) is one of the largest healthcare systems in the Midwest, headquartered in Indianapolis. IU Health operates hospitals, urgent care centers, and specialized healthcare services across the state. The system is not only a healthcare provider but also one of the largest employers in Indiana, with over 35,000 staff members.

Rolls-Royce North America

With its North American headquarters located in Indianapolis, Rolls-Royce is a key player in the aerospace and defense industries. The company manufactures aircraft engines for both commercial and military use, employing thousands in Indiana. Rolls-Royce's presence in Indiana is a testament to the state's thriving advanced manufacturing sector.

Zimmer Biomet

Zimmer Biomet, based in Warsaw, Indiana, is a global leader in musculoskeletal healthcare. The company produces orthopedic implants, surgical equipment, and biologics, with operations in over 25 countries. Zimmer Biomet's contributions to medical advancements in joint replacement and spinal care have earned it a prominent place in Indiana's life sciences sector.

Company Name	Industry	Headquarters	Global Reach
Cook Group	Medical Devices	Bloomington	Global
Zimmer Biomet	Healthcare (Orthopedics)	Warsaw	Global

Biomet Orthopedics

Biomet Orthopedics, also based in Warsaw, Indiana, was merged with Zimmer Holdings in 2015 to form Zimmer Biomet. This merger created one of the largest orthopedic companies in the world, further cementing Indiana’s reputation as a global leader in life sciences.

Simon Property Group

Simon Property Group is a real estate giant headquartered in Indianapolis. Specializing in mall development, ownership, and management, Simon Property Group is the largest real estate investment trust (REIT) in the world. The company's portfolio includes some of the most prestigious retail properties globally, including the Mall of America.

Company Name	Industry	Headquarters	Market Capitalization
Simon Property Group	Real Estate	Indianapolis	$44.35 billion

Conclusion

Indiana is home to some of the most influential companies in the world, each contributing significantly to the state's economy and employment landscape. From global pharmaceutical giants like Eli Lilly to manufacturing powerhouses like Cummins, Indiana's business environment is diverse and dynamic. These top 100 companies reflect the strength and resilience of Indiana’s economy, with a focus on innovation, sustainability, and global impact.